HomeMicrosoftOutlook6 Ways to Fix “The Set of Folders Cannot Be Opened” Error in Outlook for Windows

5.1. 6 Ways to Fix “The Set of Folders Cannot Be Opened” Error in Outlook for Windows

6 Ways to Fix “The Set of Folders Cannot Be Opened” Error in Outlook for Windows

Quick Tips
  • Open Outlook in safe mode to check if one of your add-ins is triggering the error.
  • Removing the XML files from the Outlook directory can also help fix this issue.
  • If the error persists, consider creating a new Outlook profile or running the Office repair tool.

Fix 1: Reset the Navigation Pane

Sometimes, Outlook may fail to load the navigation pane entirely and throw an error message that reads, “Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened.”

You can reset Outlook’s navigation pane to see if that fixes the problem. To do so, press the Windows + R keyboard shortcut to open the Run dialog box. Type in the following command and press Enter.

outlook.exe /resetnavpane

Fix 2: Open Outlook in Safe Mode

Opening Outlook in safe mode can help you determine whether the “The set of folders cannot be opened” error in Outlook is occurring due to a faulty add-in. Press and hold the Ctrl key on your keyboard and double-click the Outlook shortcut. Select Yes when the confirmation prompt appears.

Open Outlook in Safe Mode

If you don’t encounter any errors while using Outlook in safe mode, it means that one of your add-ins is causing the problem. To identify the problematic add-in, you will need to disable all the add-ins and re-enable them one at a time.

Step 1: Open the Outlook app and click the File menu at the top.

Outlook File Menu

Step 2: Select Options in the left pane.

Outlook Options

Step 3: In the Outlook Options window, switch to the Add-ins tab. Use the drop-down menu next to Manage and select COM Add-ins. Then, click the Go button.

Outlook Add-ins

Step 4: Uncheck the boxes to disable your add-ins and click OK.

Disable Outlook Add-ins

Restart the Outlook app after this and re-enable your add-ins one at a time until the error appears again. Once you find the problematic add-in, consider removing it.

Fix 3: Remove XML Files From Outlook Directory

Outlook uses XML files to store information about user profiles, preferences, and other essential data. If these files somehow become corrupted, Outlook may throw various errors. To fix them, you will need to remove the problematic XML files from the Outlook directory.

Step 1: Press the Windows + R keyboard shortcut to open the Run dialog box. Type the following path in the box and press Enter.

%appdata%\Microsoft\Outlook

Step 2: Locate and select XML files and then click the trash icon at the top.

Delete Outlook XML Files

Fix 4: Run the Inbox Repair Tool

Another reason why you might encounter this error is if your Outlook data files (PST or OST) have become corrupted. The Outlook offers a tool that can automatically find and fix problematic files.

Step 1: Press the Windows + E keyboard shortcut to open File Explorer and navigate to the following folder.

C:\Program Files\Microsoft Office\root\Office16

Step 2: Double-click the SCANPST.EXE file.

Scan Outlook Inbox 1

Step 3: Click Start to initiate the scan.

Outlook Inbox Repair

Step 4: If the tool finds any issues, click Repair.

Outlook Inbox Repair Tool

Fix 5: Create a New Outlook Profile

Several users on the Microsoft forum reported fixing the “The set of folders cannot be opened” error in Outlook by removing old profiles and recreating them. You can also give it a try.

Step 1: Click the search icon on the taskbar, type in registry editor, and select Run as administrator.

Open Registry Editor as Admin

Step 2: In the Registry Editor window, paste the following path in the address bar at the top and press Enter.

HKEY_CURRENT_USER\SOFTWARE\Microsoft\Office\16.0\Outlook\Profiles

Step 3: Right-click on any subkey within the Profiles key and select Delete.

Delete Outlook Profiles via Registry Editor

Step 4: Select Yes to confirm. Similarly, delete all the keys within the Profiles subkey and close the Registry Editor window.

Confirm Delete Outlook Profiles

Step 5: Click the search icon on the taskbar, type in control panel, and press Enter.

Open Control Panel on Windows

Step 6: Change the view type to Large icons and click on Mail (Microsoft Outlook).

Mail (Microsoft Outlook)

Step 7: Click the Show Profiles button.

Outlook Profiles

Step 8: Click the Add button, enter the name for the new profile, and click OK.

Create New Profile for Outlook

Step 9: In the Add Account window, enter your account details and hit Next.

Create Outlook Profile

Step 10: Select your new profile under When starting Microsoft Outlook and hit Apply.

Change Default Outlook Profile

Fix 6: Run the Office Repair Tool

Running the Office repair tool can help you troubleshoot issues with all the Office apps, including Outlook. So, if none of the above tips work, try running the Office repair tool using the steps below.

Step 1: Press the Windows key + R to open the Run dialog box. Type appwiz.cpl in the box and press Enter.

Step 2: In the Programs and Features window, select the Microsoft Office product on the list and click the Change button at the top.

Repair MS Office Suite

Step 3: Select the Online Repair option and click Repair.

Repair Office Apps

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